Scientific journal (Nuclear Medicine) Essay Example | Topics and Well Written Essays - 1000 words

Scientific journal (Nuclear Medicine) - Essay Example he application of the methods may facilitate the noninvasive imaging of therapeutic tumor responses to specific drug treatments to provide a reliable index of their potential efficacy and as a monitor of mechanisms of action in the selective destruction of tumor cells. The research article discusses the potential for the expanded use of quantitative PET molecular imaging to assess the efficacy of novel targeted therapeutics in the treatment of cancer. The use of radiolabelled biomarkers serves as a molecular tag which can be traced using PET imaging tools to delineate the molecular interactions between a targeted drug and the tumor cells destined for destruction. The implementation of the molecular tools allows researches to determine whether the drug effectively interacts with its selected target and the concentration of drug that actually reaches the tumor site following drug administration. Non-specific interactions of the drug with non-tumor tissue may also be assed using this methodology. The authors reviewed the results of several clinical trials of this methodology used to assess the efficacy of several important new classes of targeted chemotherapeutics, including protein tyrosine kinase inhibitors (PTKIs) and epidermal growth factor recep tor (EGFR) ligands. In the latter case, several drugs approved for cancer treatment by the US FDA, including lapatinib, gefitinib ,and erlotinib, were assessed using this nuclear medicine application. Each of these drugs has produced equivocal results in patients with lung cancer and other tumors that overexpress the EGFR. Several research trials involving labeled chemotherapeutics were cited and data presented indicated that in some cases, reliable data were produced by this nuclear medicine molecular assessment approach. The authors have presented a compelling theoretical argument to support the use of PET imaging technology in the molecular assessment of therapeutic responses to targeted cancer drugs. This

Formulating Analyzing & Researching Tourism Policy Essay - 3

Formulating Analyzing & Researching Tourism Policy - Essay Example The developmental policy of the Gatwick policy is to â€Å"ensure that Gatwick’s operation and development effectively address national, regional and local objectives for economically, socially and environmentally responsible development† (GAOMP p. 3). Regarding the environmental issues, special care is taken by the policy designers to address issues that are related to ‘air quality and air noise’ as well as ‘ground noise, biodiversity and resource use† (GAOMP p. 4). Similarly, it is also mandatory that the Gatwick policy gives due importance to ‘safety and security on the ground and in the air’ while designing the buildings and structures for the proposed plan. The legal limits to Gatwick policy are set by the airspace policy and air traffic control put by the UK Government and National Air Traffic services. Consequently, the new policy should give predominance to the four objectives for sustainable development. These four objectiv es include â€Å"Social progress which recognizes the needs of everyone†, â€Å"Effective protection of the environment†, â€Å"prudent use of natural resources† and â€Å"maintenance of high and stable levels of economic growth and employment† (GAOMP P. 7). The air port development also needs to take into account the developmental control guidelines set out in town and country planning legislation, circulars and guidance and should cope up with the airport design criteria set by the Civil Aviation Authority, the airport security guidelines set by the Department of Transport and the safeguard aerodrome and public safety zones (GAOMP P. 13). If the tour is not properly planned considering all the aspects it can cause many socio-economic and environmental problems. Avoiding these negative impacts must be the priority of the policy makers. The local authority support is also a significant requirement for the development.